- NEW: U.N. official says a confrontation in Aleppo "bodes ill for the people of that city"
- NEW: The UK urges Syrian President Bashar al-Assad to call off the assault
- NEW: Aid agencies are scaling back in Aleppo
- A Syrian parliamentarian from Aleppo has defected to Turkey
(CNN) -- World powers fear the prospect of a government "massacre" in Aleppo, the sprawling and densely populated Syrian city where rebels braced for more clashes with government forces Friday.
One rebel commander said plans were under way to send 300 more fighters to bolster forces in the city, where 18 of 22 rebel brigades are located. Another, Mustafa Abdullah, told CNN that rebels have set up medical clinics in Aleppo homes and have plans to transport and evacuate anyone who is wounded.
"They (government forces) want to surround Aleppo completely and send support from all sides, then start shelling rebel-controlled areas and hospitals," Abdullah said.
He spoke as throngs of protesters marched down Aleppo streets Friday, chanting and carrying signs, saying, "we stand for all the Syrian devastated cities" and "we are all Syrians."
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Syrians surround a U.N observer vehicle after placing the bodies of a girl and man on the car in Houla on Saturday, May 26, 2012. The photo is from the opposition Shaam News Network. Forty-nine children were among the 108 slaughtered in Houla on Friday, May 25, U.N. monitors say. The massacre in Houla, a suburb of the anti-government bastion of Homs, has reignited international fury against Bashar al-Assad's regime. 
The body of a slain Syrian child lies next to other shrouded bodies at a hospital mortuary in Houla on Saturday in another photo from the opposition Shaam News Network. Al-Assad's regime insists it is not behind the massacre and blames terrorist groups. Syria has attributed violence on "armed terrorist groups" throughout the 14-month-old uprising. 
Bodies of children lie in a Houla hospital morgue before their burial Saturday in another photo from Shaam News Network. Images from the town show a room crammed with mangled and bloody bodies of children -- some with their skulls torn open. 
U.N. observers visit a hospital morgue in Houla on Saturday before the burial of massacre victims. Opposition activists and residents blame al-Assad's regime for the bloodbath. 
A Houla resident shows a body to a U.N. observer at a mosque in the central Syrian town. Some U.N. Security Council members condemned the attacks "that involved a series of government artillery and tank shellings on a residential neighborhood" as well as killings of civilians by close-range gunshots. 
Syrians gather at a mass burial Saturday in Houla. "Those responsible for these brutal crimes must be held accountable," Kofi Annan, the U.N.-Arab League special envoy, said in a statement. Photos: Massacre in Syria And as demonstrations continued, President Bashar al-Assad's forces shelled neighborhoods in Aleppo with helicopters, according to the opposition Local Coordination Committees of Syria. Regime forces fired at protesters coming out of the Al-Ghafran Mosque in the city's Khaldieh district, the LCC said.
Syrian state TV said "special security authorities" destroyed five pickup vehicles equipped with machine guns used by "terrorists" in the Aleppo countryside. The report said people in the vehicles were killed and injured.
Six of 40 people slain in Syria on Friday were from Aleppo province, the LCC said. The day before, 48 of the 200 people killed in Syria violence were also from the Aleppo region, the first time since the uprising started that the region led in the number of deaths in a single day.
Aleppo, in northern Syria near Turkey, is the country's commercial capital and a World Heritage site. The CIA World Factbook says it is the nation's most populous city.
Navi Pillay, the U.N. high commissioner for human rights, said an imminent major confrontation and a buildup of forces in and around Aleppo "bodes ill for the people of that city" in light of the carnage across the nation.
Read more: Syrian town's 'Street of Death'
British Foreign Secretary William Hague said the government has started "a vicious assault" in Aleppo and urged al-Assad to call it off.
"This utterly unacceptable escalation of the conflict could lead to a devastating loss of civilian life and a humanitarian disaster. It will add to the misery being endured by the Syrian people, and plunge the country further into catastrophic civil war," he said.
Bernard Valero, a French Foreign Ministry spokesman, said his country fears that "more and more civilians will be killed in Aleppo" as military forces circle the city and prepare to launch a "devastating" military operation.
"Bashar al-Assad is about to commit another horrific crime against his own population," he said.
U.S. State Department spokeswoman Victoria Nuland on Thursday expressed "grave concerns" that Syrian forces are preparing to carry out a "massacre" in and around the city. She noted that the Aleppo region has been bombarded by Syrian fighter jets and that columns of regime tanks are reportedly prepared to attack.
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Rebel militias battling regime forces in Aleppo and other hotspots are composed largely of soldiers who have defected from the Syrian military. But there are also many civilians -- including students, shopkeepers, real-estate agents and members of the president's ruling Ba'ath party -- all trying to end four decades of Assad family rule.
Abdullah, the rebel commander in Aleppo, recalled the merciless government bombardment of the city of Homs this year as he geared up for battle. Asked if these fighters had enough ammunition to withstand a government siege, Abdullah said simply "no." He then added "it will be just like Homs" and wept at the thought.
The Aleppo fighting has political significance.
A Syrian parliamentarian from Aleppo has defected to Turkey, according to the opposition Syrian National Council. Ikhlas Badawi is the first member of the assembly elected in May to defect and the latest in a series of high-profile officials to cut ties with the regime. This follows defections by high-level Syrian diplomats to the United Arab Emirates, Cyprus and Iraq.
Andrew Tabler, a Syria expert at the Washington Institute for Near East Policy, said that if the government military effort fails in Aleppo, "it will cost the regime dearly and begin a process of contraction of regime control over Syria."
"If the regime is able to beat the rebels back, this conflict will go on far longer," he said.
As fighting raged, aid agencies scaled back their efforts in Aleppo.
A spokeswoman for the International Committee of the Red Cross -- which said it is temporarily moving some aid workers out of Syria to Beirut for security reasons -- said the organization doesn't have a presence in Aleppo at the moment. The Syrian Arab Red Crescent has had to suspend some of its activities.
"The situation there is extremely volatile," the ICRC said. "Several schools in Aleppo have been opened to host displaced families, and the local SARC volunteers have provided some relief items (mattresses, hygiene products and food). However, humanitarian needs are on the rise."
Outside Aleppo, battles between regime forces and rebels raged. Heavy shelling rocked other cities, including Damascus, Daraa, Idlib and Homs, the Local Coordination Committees of Syria said. Ten people died in Daraa and nine in Damascus and its suburbs.
People fleeing violence were on the move. A group of Syrian refugees came under fire Thursday night while crossing the border into Jordan, said Petra, the Jordanian state news agency. A child was killed during the incident, according to Samih Maaytah, the minister of state for media affairs.
The Syrian crisis started in March 2011 when a government crackdown on peaceful protesters morphed into a nationwide uprising against the regime.
The LCC says more than 16,000 people have been killed in the conflict. The U.N. secretary-general said this week that almost 17,000 people have died.
CNN's Saad Abedine, Ivan Watson, Faith Karimi, Samira Said and Joe Sterling contributed to this report.
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